What is Liposomal Technology?

 

 

 

 

 

 

 

About Liposomal Technology

Liposomal technology has an internal structure consisting of water and water-soluble active ingredients and consists of a phospholipid bilayer membrane, which increases nutrient persistence and absorption rate.

 

Key Technology Features

Molecular Sculpting of Flexible Nano Spheres (FS):

• High-energy mechanical forces sculpt phospholipid complexes into flexible nanospheres.

• Particle size reduction improves stability and dispersibility.

• FS offer membrane fluidity, critical for liposomal stability in varying biological environments (pH, ionic strength).

• Enhances the encapsulation of both hydrophilic and hydrophobic molecules.

 

Flexibility Benefits:

• Easier functionalization with targeting ligands (antibodies, peptides).

• Maintains stability and controlled release properties.

 

Uniqueness vs. Conventional Liposomes:

• Smaller and uniform particle size (~189 nm vs. 335 nm for Lypo-C).

• Higher zeta potential (-31.37 mV vs. -19.2 mV), indicating stronger electrostatic stabilization and reduced aggregation.

• Spherical, smooth particles without aggregation (confirmed by SEM & TEM).

 

Scientific Validation

Characterization Methods:

• Scanning Electron Microscopy (SEM)

• Transmission Electron Microscopy (TEM)

• Dynamic Light Scattering (DLS)

• Zeta Potential (ZP)

 

Stability:

• Heat-stable up to 100°C.

 

Permeation & Bioavailability Studies:

• CaCo2 cell line permeation studies: 2.8x to 3.5x enhanced permeability across various nutrients (CoQ10, Vitamin D3, Zinc Bisglycinate, Iron Bisglycinate).

• Human bioavailability studies:

  • Vitamin C absorption was 7.62 times higher and 6.29 times faster than conventional Vitamin C.

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